Systems BiologyAtherosclerosisPeer-reviewed
Agent-Based Modeling Predicts HDL-independent Pathway of Removal of Excess Surface Lipids from Very Low Density Lipoprotein
Yared Paalvast, Jan Albert Kuivenhoven, Barbara M. Bakker, Albert Kornelis Groen
The paper develops an agent-based model of lipoprotein metabolism to investigate how high plasma triglycerides lead to low HDL cholesterol, finding that excess surface lipids from VLDL are cleared independently of HDL.
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