Author

Albert Kornelis Groen

Amsterdam UMC Location University of AmsterdamORCID 0000-0002-9942-1854Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1

Frequent Co-Authors

Abraham Stijn MeijnikmaniD· 2 shared Arnold W. J. M. van de LaariD· 2 shared Max NieuwdorpiD· 2 shared Sjoerd C. BruiniD· 2 shared Victor E. A. GerdesiD· 2 shared Annika LundqvistiD· 1 shared Barbara M. BakkeriD· 1 shared Boyang JiiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersSystems Biology

Abraham Stijn MeijnikmanORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintOct 15, 2025

Adipose Tissue Inflammation, Oxidative Stress, and Altered Adipogenesis Are Drivers of Dyslipidemia - A Multi-Omics Overview of Dyslipidemia in Obesity

Max S. Z. Zwartjes, Patrick A. de Jonge, Arnold W. J. M. van de Laar…·Max Nieuwdorp

This study investigates the role of adipose tissue in dyslipidemia through multi-omics analysis of patients with obesity, identifying inflammation, oxidative stress, and altered adipogenesis as key drivers.

DOI 10.1101/2025.10.15.682716

humanbulk RNA-seq

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Systems BiologybioRxivPreprintApr 26, 2022

Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota

Peishun Li, Boyang Ji, Dimitra Lappa…·Jens Nielsen

The paper analyzes metabolic responses to a mixed meal test in an obese cohort, linking tissue metabolism with gut microbiota changes and identifying potential biomarkers for T2DM.

2 citations

humanmetabolomics

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Systems BiologyAtherosclerosisPeer-reviewedAug 1, 2018

Agent-Based Modeling Predicts HDL-independent Pathway of Removal of Excess Surface Lipids from Very Low Density Lipoprotein

Yared Paalvast, Jan Albert Kuivenhoven, Barbara M. Bakker, Albert Kornelis Groen

The paper develops an agent-based model of lipoprotein metabolism to investigate how high plasma triglycerides lead to low HDL cholesterol, finding that excess surface lipids from VLDL are cleared independently of HDL.

1 citation

experimental assay

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