Cell BiologyAdvanced SciencePeer-reviewed
Cholesterol metabolism modulation facilitates CAR-T induced killing of ovarian cancer
Chinmayee Vallabh Prabhu Dessai, Zhuoying Huang, Haonan Lin…·Ji‐Xin Cheng
This study shows that modulating cholesterol metabolism in ovarian cancer cells enhances CAR-T cell cytotoxicity by disrupting lipid storage mechanisms.