Author

Jikui Guan

University of GothenburgORCID 0000-0003-1723-0307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:Drosophila· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Organism:zebrafish· 1

Frequent Co-Authors

Ruth Helen PalmeriD· 2 shared Adam Lehnberg· 1 shared Agata AniszewskaiD· 1 shared Ajeet Pratap SinghiD· 1 shared Andrey FadeeviD· 1 shared Bengt HallbergiD· 1 shared Christiane Nüsslein‐VolhardiD· 1 shared Dan Emil LindiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Ruth Helen PalmerORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 17, 2025

ALK/ATR combination therapy is effective in neuroblastoma mouse tumors driven by MYCN

Marcus Borenäs, Dan Emil Lind, Adam Lehnberg…·Ruth Helen Palmer

This study shows that combining ATR and ALK inhibitors improves survival in MYCN-amplified neuroblastoma mouse models lacking ALK mutations.

1 citation

mouseexperimental assay

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Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 9, 2018

ALKALs are in vivo ligands for ALK family Receptor Tyrosine Kinases in the neural crest and derived cells.

Andrey Fadeev, Patricia Mendoza-García, Uwe Irion…·Ruth Helen Palmer

The paper demonstrates that ALKALs activate ALK/LTK family receptors and are involved in neural crest development using zebrafish and Drosophila models.

76 citationstop 4%

zebrafishDrosophila

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