Molecular BiologybioRxivPreprint
Autophagy limits inflammatory gene expression through targeting of nuclear p65/RelA by LC3 and p62 for lysosomal degradation
Cristina Brischetto, Patrick Mucka, Eva Kaergel, Claus Scheidereit
This study identifies a mechanism by which autophagy regulates NF-κB-driven inflammation through lysosomal degradation of nuclear p65 via LC3 and p62.
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