Jonny P Flint

This study identifies distinct frailty domains with varying causal relationships to Alzheimer's disease using genetic methods.

This paper uses multi-polygenic scores to predict frailty and its trajectories, identifying chronic pain, rheumatoid arthritis, and educational attainment as key pathways.

This study validates a polygenic risk score for frailty using two independent cohorts, showing it predicts frailty at early ages with moderate variance explained.