Author

Caroline Howard

Wellcome Sanger InstituteORCID 0000-0003-1739-6569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:database / resource· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Mark BlaxteriD· 2 shared Abitha ThomasiD· 1 shared Adam BatesiD· 1 shared Akira SatoiD· 1 shared Alex D. TwyfordiD· 1 shared Amy DentoniD· 1 shared Benjamin G. JacksoniD· 1 shared Carlos ReyneliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersEvolutionary Biology

Mark BlaxterORCID

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3 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintJun 20, 2026

Hybridisation and herbivory fuel Amazonian tree radiations

Rowan Schley, Alex D. Twyford, María‐José Endara…·R. Toby Pennington

This study shows hybridisation enables Amazonian trees to rapidly evolve chemical defences against herbivores, driving diversification in response to shifting herbivore communities.

DOI 10.64898/2026.06.17.732868

plant (other)whole-genome sequencing

𝕏 PostBluesky

GenomicsConservation LettersPeer-reviewedJul 1, 2025

An updated DNA barcoding tool for Aloe vera and related CITES-regulated species

Yannick Woudstra, Paul Rees, Solofo E. Rakotoarisoa…·Olwen M. Grace

The paper introduces an updated DNA barcoding tool for Aloe vera and related CITES-regulated species, validated for accurate species identification using 189 nuclear markers.

4 citations

plant (other)DNA methylation

𝕏 PostBluesky

Molecular BiologybioRxivPreprintApr 11, 2025

✦ In-depth digest

On the path to reference genomes for all biodiversity: lessons learned and laboratory protocols created in the Sanger Tree of Life core laboratory over the first 2000 species

Caroline Howard, Amy Denton, Benjamin G. Jackson…·Mara Lawniczak

Across 4883 species, standardised high-molecular-weight DNA extraction passed 96% of chordate and 91% of plant species, while fungi failed at 34.2%; ultra-low-input PacBio libraries rescue many low-yield samples.

665 citations

multiple specieslong-read sequencing

𝕏 PostBluesky