NeuroscienceCell chemical biologyPeer-reviewed
A Toxic RNA Catalyzes the Cellular Synthesis of Its Own Inhibitor, Shunting It to Endogenous Decay Pathways
Raphael I. Benhamou, Alicia J. Angelbello, Eric T. Wang, Matthew David Disney
This paper shows that toxic RNA repeats can catalyze the synthesis of their own inhibitors, leading to degradation and rescue of DM2-related defects.