BioinformaticsbioRxivPreprint
Bacterial DNA methylation amplifies the shared A-to-G and G-to-A substitution bias in nanopore sequencing
Xudong Liu, Qiutao Ding, Yanwen Shao…·Runsheng Li
The paper identifies a shared A-to-G and G-to-A substitution bias in nanopore sequencing, amplified by bacterial DNA methylation, and shows this bias is concentrated around methylation motifs.