Xudong Liu

The paper identifies a shared A-to-G and G-to-A substitution bias in nanopore sequencing, amplified by bacterial DNA methylation, and shows this bias is concentrated around methylation motifs.

Giraffe is a tool for comparative analysis and visualization of long-read sequencing data across multiple samples and platforms, showing Oxford Nanopore duplex reads outperform PacBio HiFi in homopolymer identification and GC evenness.