Author

Mechthild Krause

German Cancer Research CenterORCID 0000-0003-1776-9556Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anna DubrovskaiD· 2 shared Annett LingeiD· 2 shared Ayşe Sedef KöseeriD· 2 shared Ielizaveta GorodetskaiD· 2 shared Uğur KahyaiD· 2 shared Vasyl Lukiyanchuk· 2 shared Aldo Leal‐EgañaiD· 1 shared Ananya ChoudhuryiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Anna DubrovskaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 22, 2025

Glutamine transporters regulate prostate cancer radiosensitivity through NUPR1-mediated stress response

Uğur Kahya, Vasyl Lukiyanchuk, Ielizaveta Gorodetska…·Anna Dubrovska

This study shows that glutamine transporters regulate prostate cancer radiosensitivity via NUPR1-mediated stress response, with targeting these transporters enhancing radiosensitivity and improving treatment outcomes.

DOI 10.1101/2025.04.22.650063

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyJournal of Experimental & Clinical Cancer ResearchPeer-reviewedMar 23, 2025

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

Ielizaveta Gorodetska, Vasyl Lukiyanchuk, Marta Gawin…·Anna Dubrovska

This study identifies MMP11 as a blood-based biomarker for prostate cancer progression, regulated by the ALDH1A1-TGF-β1 signaling pathway.

11 citations

humanbulk RNA-seq

𝕏 PostBluesky