Author

Anna Dubrovska

Helmholtz-Zentrum Dresden-RossendorfORCID 0000-0002-3375-1500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ielizaveta GorodetskaiD· 3 shared Annett LingeiD· 2 shared Ayşe Sedef KöseeriD· 2 shared Mechthild KrauseiD· 2 shared Uğur KahyaiD· 2 shared Vasyl Lukiyanchuk· 2 shared Aldo Leal‐EgañaiD· 1 shared Alexandra Kegler· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

Ielizaveta GorodetskaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

3D Microphysiological Tumor Model for Dual-Targeting CAR T Cell Immunotherapy

Xuan Peng, Željko Janićijević, Liliana Rodrigues Loureiro, Lydia Hoffmann, Poh Soo Lee, Isli Çela, Benjamin Kruppke, Alexandra Kegler, Anja Feldmann, Ielizaveta Gorodetska, Anja Madleine Markl, Anna Dubrovska, Anne Kathrin Offermann, Michael Philipp Bachmann, Larysa Baraban

This paper develops a 3D tumor model to test dual-targeting CAR T cell therapy and shows its effectiveness against solid tumors.

Advanced Science · Jul 24, 2025Peer-reviewedBioengineering

Glutamine transporters regulate prostate cancer radiosensitivity through NUPR1-mediated stress response

Uğur Kahya, Vasyl Lukiyanchuk, Ielizaveta Gorodetska, Matthias M Weigel, Ayşe Sedef Köseer, Berke Alkan, Dragana Savic, Annett Linge, Steffen Löck, Mirko Peitzsch, Ira Skvortsova, Mechthild Krause, Anna Dubrovska

This study shows that glutamine transporters regulate prostate cancer radiosensitivity via NUPR1-mediated stress response, with targeting these transporters enhancing radiosensitivity and improving treatment outcomes.

bioRxiv · Apr 22, 2025 · PreprintCancer Biology

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

Ielizaveta Gorodetska, Vasyl Lukiyanchuk, Marta Gawin, Myroslava Y. Sliusar, Annett Linge, Fabian Lohaus, Tobias Hölscher, Kati Erdmann, Susanne Fuessel, Angelika Borkowetz, Anna Wojakowska, Daniel Fochtman, Mark Reardon, Ananya Choudhury, Yasmin Antonelli, , Anna Dubrovska

This study identifies MMP11 as a blood-based biomarker for prostate cancer progression, regulated by the ALDH1A1-TGF-β1 signaling pathway.

Journal of Experimental & Clinical Cancer Research · Mar 23, 2025Peer-reviewedCancer Biology