Yue Huang

This study demonstrates that combined editing of CACCC and TGACCA motifs can nearly reverse the γ- to β-globin switch by redirecting enhancer-promoter interactions.

This study identifies Prmt1-mediated Klf4 methylation as critical for lineage segregation between epiblast and primitive endoderm in mouse embryos.

This study shows heat shock reduces Oct4 levels in mouse blastocysts and stem cells via the ubiquitin-proteasome pathway involving Dapk1 and Pin1.