Author

Guanghui Yang

Howard Hughes Medical InstituteORCID 0000-0002-2784-521XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Guanghui Yang1 paper

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Organism:C. elegans· 1

Frequent Co-Authors

Xin CheniD· 2 shared Abhyudai SinghiD· 1 shared Binbin Ma· 1 shared Binbin MaiD· 1 shared Brendon E. M. DavisiD· 1 shared Charles Wu· 1 shared Di WuiD· 1 shared Fei Chen· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

Xin ChenORCID

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4 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedMar 23, 2026

Asymmetric Histone Inheritance Regulates Olfactory Stem Cell Fates During Regeneration

Binbin Ma, Guanghui Yang, Jonathan Yao…·Xin Chen

This study shows that asymmetric histone inheritance in olfactory stem cells during regeneration affects cell fate and tissue repair in mice.

2 citationstop 4%

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Developmental BiologybioRxivPreprintSep 19, 2024

Modulating DNA Polα Enhances Cell Reprogramming Across Species

Rajesh Ranjan, Binbin Ma, Ryan J. Gleason…·Xin Chen

This study shows that reducing DNA Polα levels enhances cell reprogramming across species, improving fertility and tissue regeneration without affecting lifespan.

1 citation

DrosophilaC. elegans

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Developmental BiologybioRxivJul 27, 2022

Germ-cell specific eIF4E1B regulates maternal RNA translation to ensure zygotic genome activation

Guanghui Yang, Qiliang Xin, Iris Feng…·Jurrien Dean

The paper shows that eIF4E1B regulates maternal mRNA translation to enable zygotic genome activation by protecting chromatin remodeling and reprogramming factor mRNAs from degradation.

25 citations

mousebulk RNA-seq

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Molecular BiologyNucleic Acids ResearchPeer-reviewedJan 25, 2022

Klf4 methylated by Prmt1 is required for lineage segregation of epiblast and primitive endoderm

Zhenyu Zuo, Guanghui Yang, Haiyu Wang…·Ye Zhang

This study identifies Prmt1-mediated Klf4 methylation as critical for lineage segregation between epiblast and primitive endoderm in mouse embryos.

12 citations

mousebulk RNA-seq

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