Aging: an inevitable road toward gut microbiota pathoadaptation
Rita Melo-Miranda, Ana Pinto, Hugo C. Barreto, Catarina S. H. Jesus, Isabel Gordo, Iola F. Duarte, Ana Sousa
This study shows that even in healthy aging conditions, gut commensals acquire pathoadaptive traits, suggesting that aging increases selection for pathobionts regardless of colonization resistance.
bioRxiv · Jan 29, 2025 · PreprintEvolutionary Biology