Isabel Gordo

The paper shows that chronic gut inflammation drives bacterial and prophage hybridization in E. coli, leading to new genetic lineages associated with inflammatory bowel disease.

This study shows that even in healthy aging conditions, gut commensals acquire pathoadaptive traits, suggesting that aging increases selection for pathobionts regardless of colonization resistance.

When pyoverdine and elastase are both needed, a pvdS mutant outcompetes the lasR cheater in P. aeruginosa and averts population collapse; a cost-ratio model with quorum sensing explains this.