Rebecca Sebastian

This study compares synaptic effects of NRXN1 deletions in ASD and SCZ iPSC models, finding distinct synaptic and network impairments in ASD.

This paper introduces a device to generate morphogen gradients for creating patterned brain organoids, revealing distinct cell types and long-term stability.

This study shows NRXN1 deletions affect brain development differently in specific cell types and genetic backgrounds, leading to synaptic dysfunction in organoids.