Author

Danny McSweeney

University of Massachusetts Amherst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

ChangHui PakiD· 2 shared Zhiping P. PangiD· 2 shared Bruce J. AronowiD· 1 shared Ethan Howell· 1 shared Fumiko Ribbe· 1 shared Jay EnglishiD· 1 shared Jinghui GengiD· 1 shared Kang JiniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

ChangHui PakORCID

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2 papers

Recent·Most cited

Distinct Synaptic Mechanisms Drive NRXN1 Variant-Mediated Pathogenesis in iPSC-Derived Neuronal Models of Autism and Schizophrenia

Jay English, Danny McSweeney, Jinghui Geng, Ethan Howell, Fumiko Ribbe, Matthew Hinderhofer, Lydia Proskauer, Rebecca Sebastian, Le Wang, Tal Sharf, Zhiping P. Pang, ChangHui Pak

This study compares synaptic effects of NRXN1 deletions in ASD and SCZ iPSC models, finding distinct synaptic and network impairments in ASD.

bioRxiv · Jul 18, 2025 · PreprintNeuroscience

Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons

Danny McSweeney, Rafael Gabriel, Kang Jin, Zhiping P. Pang, Bruce J. Aronow, ChangHui Pak

This study shows that CASK loss disrupts synaptic transmission and network synchronicity in mature human cortical neurons but not synapse formation or neurite complexity.

bioRxiv · Feb 14, 2022 · PreprintNeuroscience