Author

Jacquelyn M. Roger

University of California, Santa CruzORCID 0000-0003-1823-0421Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Geoffrey LyleiD· 1 shared Bryan P. ThornlowiD· 1 shared David H. HaussleriD· 1 shared Drew ThompsoniD· 1 shared Du Linh LamiD· 1 shared Ellen Towle KephartiD· 1 shared Henry Z. GongiD· 1 shared Holly C. BealeiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

A. Geoffrey LyleORCID

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2 papers

Recent·Most cited

GenomicsGigaSciencePeer-reviewedMar 1, 2021

The case for using Mapped Exonic Non-Duplicate (MEND) read counts in RNA-Seq experiments: examples from pediatric cancer datasets

Holly C. Beale, Jacquelyn M. Roger, Matthew A. Cattle…·Olena M. Vaske

The paper evaluates the informativeness of reads in bulk RNA-Seq datasets and recommends using MEND reads for accurate gene expression quantification in pediatric cancer studies.

8 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsProceedings of the National Academy of SciencesPeer-reviewedAug 20, 2018

Transfer RNA genes experience exceptionally elevated mutation rates

Bryan P. Thornlow, Josh Hough, Jacquelyn M. Roger…·Russell B Corbett-Detig

The paper shows tRNA genes have much higher mutation rates than the genome average, driven by transcription-associated mutagenesis and purifying selection.

56 citations

humanmultiple species

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