Michael L. Hines

The paper modernizes the NEURON simulator to improve sustainability, portability, and performance through new tools and optimizations.

The paper records glutamate-mediated dendritic plateau potentials in rat cortical pyramidal neurons and uses a model to show these potentials alter neuronal state, increasing excitability and enabling rapid response to subsequent inputs.

The paper introduces HNN, a software tool that interprets the cellular and network origin of human MEG/EEG data using a neocortical circuit model.

Open Source Brain provides a platform for visualizing, simulating, and collaboratively developing standardized neuronal and circuit models to improve model transparency and reproducibility.

NetPyNE is a tool for creating multiscale neuronal network models in NEURON using declarative specifications, enabling efficient simulation and analysis of brain circuits.