Author

Simon Fontaine

University of MichiganORCID 0000-0003-1835-1231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Approach:statistical model· 1

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Gen LiiD· 1 shared Hui JiangiD· 1 shared Mukai WangiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBioinformatics

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1 paper

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedNov 1, 2024

ADAPT: Analysis of Microbiome Differential Abundance by Pooling Tobit Models

Mukai Wang, Simon Fontaine, Hui Jiang, Gen Li

ADAPT improves microbiome differential abundance analysis by addressing zeros and compositionality using Tobit models, showing better false discovery rate control and power in synthetic data and real 16S rRNA and shotgun metagenomics datasets.

9 citations

metagenomicsstatistical model

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