Hui Jiang

The paper characterizes HPV integration structures in oropharyngeal cancer and links Type2 integration to oncogenic features and aggressive tumor behavior.

The paper introduces MCMC-CE, an algorithm for estimating small right-tail probabilities of quadratic forms, showing improved accuracy and efficiency in genomics applications.

This study compares the acute effects of three exercise intensities on subcutaneous adipose tissue transcriptome in regular exercisers, finding intensity-specific gene expression changes and common pathways involved in cardiometabolic health.

This study identifies the MRTFA/SRF pathway as a regulator of quiescence in cancer and shows that inhibiting it induces quiescence and reduces tumor growth.

ADAPT improves microbiome differential abundance analysis by addressing zeros and compositionality using Tobit models, showing better false discovery rate control and power in synthetic data and real 16S rRNA and shotgun metagenomics datasets.

The paper uses EC-TRAP to analyze endothelial cell translatomes across vascular beds, revealing heterogeneity in gene expression and improved detection of low-abundance transcripts.

This paper introduces a QconCAT-based proteomics method to measure allele-specific protein expression (ASPE) and identifies cis-regulatory variants affecting UGT2B15 in human livers.

This study evaluates the accuracy, reproducibility, and bias of small RNA-seq across five protocols and nine labs, finding protocol-specific bias that can be mitigated with adapters and computational corrections.