Xinhui Li

This study establishes a mouse model of cyclic uremia without kidney injury, showing it drives cardiovascular disease and immunosenescence independently of traditional risk factors.

MitoSort uses mtDNA germline variants to accurately demultiplex pooled single-cell data and detect doublets, outperforming existing methods for scRNA-seq in mtscATAC-seq.

ILnc is a method using lncRNA signatures to estimate immune cell infiltration in tumors, showing higher accuracy than protein-coding gene signatures and revealing associations with clinical outcomes.