Author

Annabelle Lewis

Brunel University of LondonORCID 0000-0003-1876-1927Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Eloise ClarksoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

1 paper

Recent·Most cited

Cancer BiologyMolecular OncologyPeer-reviewedMay 28, 2025

BMP antagonist CHRDL2 enhances the cancer stem cell phenotype and increases chemotherapy resistance in Colorectal Cancer

Eloise Clarkson, Annabelle Lewis

This study shows that CHRDL2 overexpression in CRC cells enhances chemotherapy resistance and stem-cell properties by boosting DNA repair and WNT signaling.

6 citations

humanbulk RNA-seq

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