Hao Jiang

This study shows that ASXL1 mutations promote cancer by unleashing phase separation, which enhances gene activation and leukemogenesis.

This study shows that DPY30, an epigenetic modulator, controls hematopoietic stem cell function by regulating energy metabolism and genome integrity through H3K4 methylation.

This study shows that Dpy30, a component of H3K4 methyltransferase complexes, is essential for maintaining self-renewal and differentiation of postnatal neural stem and progenitor cells.