Alireza Khodadadi‐Jamayran

This study shows that ECM proteoglycans lumican and biglycan enhance antiviral immunity in HSV-1 corneal infections by promoting immune cell recruitment and cytokine production.

The paper shows that patient-derived IgG from those with severe immune-related colitis amplifies inflammation during immune checkpoint blockade in humanized FcγR mice.

This study shows cohesin-mediated chromatin remodeling is essential for dendritic cell differentiation and function, particularly antigen cross-presentation and IL-12 secretion.

The paper examines how B-cell subsets in ocrelizumab-treated multiple sclerosis patients influence vaccine responses to SARS-CoV-2, identifying specific B-cell populations associated with immune response variability.

This study demonstrates that targeting newly discovered surface-bound DNA and RNA receptors on leukocytes with Leukocyte-Tells enhances immune cell functions, showing significantly higher antimicrobial and anticancer activities than control leukocytes.

The paper shows that Dicer/miRNAs in late retinal progenitor cells are essential for proper postnatal retinal development and function.

The paper investigates the regulatory role of TezRs in Staphylococcus aureus gene transcription and identifies differentially expressed genes and pathways following TezR destruction.

The paper shows that inactivating Teazeled receptors in human leukocytes increases production of antimicrobial and anticancer compounds, with enhanced activity and stability.

The paper shows extracellular RNA regulates bacterial directional migration, and its destruction triggers 'panic state' migration in biofilms.

The paper assembles and annotates the genome of the singing mouse, using single nuclei sequencing to identify cell types in a brain region involved in song coordination.

This study shows that Nova proteins, through activity-dependent alternative splicing, are essential for the maturation and connectivity of somatostatin interneurons.

The paper shows that PRC1 maintains neuronal subtype identity independently of PRC2, by preserving chromatin topology and transcriptional memory during differentiation.

The paper introduces KNetL, a graph drawing-based dimensionality reduction method to better identify hidden cell communities in single-cell sequencing data.

The paper introduces two batch alignment methods for single-cell RNA sequencing to address drop-out issues and improve clustering accuracy across batches.

This study shows that DPY30, an epigenetic modulator, controls hematopoietic stem cell function by regulating energy metabolism and genome integrity through H3K4 methylation.

This study identifies Rbfox1 as a cell-type-specific splicing regulator that shapes efferent connectivity in cortical interneurons through alternative splicing programs.