Author

Maria Latacz

University of CologneORCID 0000-0002-0766-8236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Ammon E. PoseyiD· 1 shared Angela Vicente-LuqueiD· 1 shared Bi ShiiD· 1 shared Charlotte BruzeauiD· 1 shared Claus Moritz GraefiD· 1 shared Elı́as CampoiD· 1 shared Ferran NadeuiD· 1 shared Francesco PalombaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

Ammon E. PoseyORCID

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2 papers

Recent·Most cited

Unleashed condensation by recurrent mutations of an epigenetic regulator promotes cancer

Yansu Song, Yi Hao, Maria Latacz, Marta Cykowiak, Julia Kirylczuk, Xuebo Quan, Francesco Palomba, Songwei Ni, Linjie Liu, Jing Hu, Bi Shi, Ammon E. Posey, Qiaoli Li, Haoran Yuan, Jie Sun, , Hao Jiang

This study shows that ASXL1 mutations promote cancer by unleashing phase separation, which enhances gene activation and leukemogenesis.

bioRxiv · Feb 20, 2026 · PreprintBiochemistry

Establishment and Characterization of a CCND1-Rearranged Non-Mantle Cell Lymphoma Cell Line and Patient-Derived Xenograft Model

Claus Moritz Graef, Moritz Reese, Angela Vicente-Luque, Nicolas Mönig, Charlotte Bruzeau, Ferran Nadeu, Maria Latacz, Johanna I. Bihler, Jörn Meinel, Maria Cartolano, Martin Peifer, Sílvia Beà, Elı́as Campo, Melanie Thelen, Paul Jan Bröckelmann, Ron Daniel Jachimowicz

The paper establishes and characterizes a patient-derived cell line and xenograft model for a CCND1-rearranged non-Mantle Cell Lymphoma, showing they recapitulate tumor biology and drug resistance.

Leukemia · Jan 26, 2026Peer-reviewedCancer Biology