ImmunologyImmunityPeer-reviewed
Human Anti-Glycan Reactivity is Driven by the Selection of B cells Utilizing Private Antibody Gene Rearrangements that are Affinity Maturated in Germinal Centers
J. Stewart New, Christopher Fucile, Amanda R. Callahan…·Rodney Glenn King
The paper analyzes the human anti-GlcNAc B cell repertoire using BCR cloning and single-cell transcriptomics, finding germinal center-driven affinity maturation and diverse glycan specificity.