Author

Alexander F. Rosenberg

University of Alabama at Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:human· 3 Assay:flow cytometry· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

Christopher D. SchareriD· 2 shared Christopher FucileiD· 2 shared Troy D. RandalliD· 2 shared Amanda R. Callahan· 1 shared Anoma NelloreiD· 1 shared Barbara J. KlockeiD· 1 shared Betty J. Mousseau· 1 shared Charles O. ElsoniD· 1 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

Christopher D. ScharerORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Jump-starting the T cell response in established tumors

Tyler R. McCaw, Mingyong Liu, Christopher D. Scharer, Jeremy M. Boss, Tian Mi, Alexander F. Rosenberg, Mei Li, Rebecca Christian Arend, Donald J. Buchsbaum, James M. Markert, Troy D. Randall

This study shows that entinostat enhances CD8+ T cell responses in tumors but only when administered during a specific window after T cell activation, and this effect can be restored by prior oncolytic virus treatment.

bioRxiv · Jun 1, 2026 · PreprintImmunology

Comprehensive characterization of V(D)J recombination from long-read transcriptomic data with VDJcraft

Kaili Hu, Alexander F. Rosenberg, Yuwei Song, Chia-Hsuan Fan, Zishan Peng, Min Gao, Zechen Chong

VDJcraft is a pipeline for analyzing V(D)J recombination from long-read transcriptome data, showing improved accuracy and novel gene subclass discovery.

bioRxiv · Apr 5, 2026 · PreprintBioinformatics

Human Anti-Glycan Reactivity is Driven by the Selection of B cells Utilizing Private Antibody Gene Rearrangements that are Affinity Maturated in Germinal Centers

J. Stewart New, Christopher Fucile, Amanda R. Callahan, Julia N. Burke, Randall S. Davis, Wayne L. Duck, Alexander F. Rosenberg, John F. Kearney, Rodney Glenn King

The paper analyzes the human anti-GlcNAc B cell repertoire using BCR cloning and single-cell transcriptomics, finding germinal center-driven affinity maturation and diverse glycan specificity.

Immunity · Mar 1, 2026Peer-reviewedImmunology

Terminally Differentiated Influenza-Specific Effector Memory B Cells Circulate after Live Attenuated Influenza Vaccination

Anoma Nellore, Christopher Fucile, Christopher D. Scharer, Jack T. Geer, Jacey D Lemonds, Betty J. Mousseau, Fen Zhou, Esther Zumaquero, Jobaida Akhter, Ellie N. Ivanova, Page Murray, Valeria Estrada Navarro, Paul Goepfert, Ralf Duerr, Ramin S. Herati, , Troy D. Randall

This study identifies circulating HA+ IgDneg memory B cells after LAIV, finding they differ in transcriptional profiles and functional capacity compared to IIV-elicited cells.

bioRxiv · Jan 21, 2026 · PreprintImmunology

Diversity of motility gene signatures distinguishes commensal Clostridiathat elicit divergent host immune responses

Lennard Wayne Duck, Melissa S. Jennings, Jung-Shan Hsu, Covenant Femi Adeboboye, E. Leighann Morgan, Kiarra J. Coger, Barbara J. Klocke, Dave D. Hill, Katie L. Alexander, Alexander F. Rosenberg, Goo Lee, Qing Sheng Zhao, Charles O. Elson, Craig L. Maynard

The paper identifies distinct motility gene signatures in Clostridia that correlate with divergent immune responses, showing one group promotes inflammation while another induces tolerance.

bioRxiv · Jul 18, 2025 · PreprintImmunology