Zichang Xu

The paper shows that ZAP-70 mutations in mice lead to a shift in T cell repertoires, with pathogenic Th17 cells resembling Tregs and contributing to autoimmune arthritis.

This paper develops a novel representation of adaptive immune receptors to improve disease classification from blood samples, achieving higher accuracy for infectious disease, autoimmunity, and cancer.

InterClone stores, searches, and clusters adaptive immune receptor repertoires, demonstrating its utility in analyzing SARS-CoV-2 antibodies and TCRs from different donor groups.

This study improves epitope prediction by integrating AlphaFold with the AbAdapt pipeline, showing better prediction of antibody-specific epitope residues.