Author

Rahul S. Samant

Babraham InstituteORCID 0000-0003-1952-259XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Harvey E. JohnstoniD· 2 shared Andrew Michael FreyiD· 1 shared Estelle WuiD· 1 shared Gaurav BarveiD· 1 shared Hanneke OkkenhaugiD· 1 shared Hayley L. CarriD· 1 shared Matthias TrostiD· 1 shared Rachel E. HodgsoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Harvey E. JohnstonORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 15, 2026

Ubi-SCAPE enables deep exploration of the poly-ubiquitylome

Harvey E. Johnston, Andrew Michael Frey, Gaurav Barve…·Rahul S. Samant

The paper introduces Ubi-SCAPE, a method to purify poly-ubiquitylated proteins with high specificity, reducing contaminants and improving reproducibility.

DOI 10.64898/2026.02.13.703496

proteomicsexperimental assay

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Cell BiologybioRxivPreprintSep 7, 2025

Declining intracellular proteostasis capacity drives misfolded protein secretion in senescent human cells.

Todd Watts, Harvey E. Johnston, Yasmeen Al-Mufti…·Rahul S. Samant

This study shows that senescent human cells secrete misfolded proteins via the endo-lysosomal system, driven by DNAJC5 and reduced intracellular proteostasis.

1 citation

humanproteomics

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