Molecular BiologybioRxivPreprint
Leucine suppresses glucagon secretion from pancreatic islets by directly modulating alpha-cell cAMP
Emily R. Knuth, Hannah R. Foster, Erli Jin, Matthew J. Merrins
This study shows leucine suppresses glucagon secretion from pancreatic islets by reducing cAMP, with effects dependent on mitochondrial anaplerosis via glutamate dehydrogenase.