Author

Umamaheswar Duvvuri

University of PittsburghORCID 0000-0003-1968-3756Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Aaron T. MayeriD· 2 shared Alexandro E. TrevinoiD· 2 shared Ann Marie EgloffiD· 2 shared Eric WuiD· 2 shared Gregory W. CharvilleiD· 2 shared H. Blaize D’AngioiD· 2 shared Honesty KimiD· 2 shared James ZouiD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Aaron T. MayerORCID

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3 papers

Recent·Most cited

Cancer BiologyCell Death and DiseasePeer-reviewedAug 8, 2025

Epidrug Screening Identifies Type I PRMT Inhibitors as Modulators of Lysosomal Exocytosis and Drug Sensitivity in Cancers

Baris Sergi, Neslihan Yuksel-Catal, Selahattin Can Özcan…·Ceyda Acilan

This paper screens epigenetic drugs to identify Type I PRMT inhibitors that inhibit lysosomal exocytosis and enhance chemotherapy efficacy in cancer.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsPNAS NexusPeer-reviewedMay 19, 2023

7-UP: generating in silico CODEX from a small set of immunofluorescence markers

Eric Wu, Alexandro E. Trevino, Zhenqin Wu…·James Zou

7-UP generates in silico 40-plex CODEX data from a 7-plex mIF panel using cellular morphology, enabling cell type classification and survival prediction across diverse samples.

25 citations

humanspatial transcriptomics

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BioinformaticsNature Biomedical EngineeringPeer-reviewedNov 10, 2022

SPACE-GM: geometric deep learning of disease-associated microenvironments from multiplex spatial protein profiles.

Zhenqin Wu, Alexandro E. Trevino, Eric Wu…·James Zou

SPACE-GM identifies spatial motifs in cancer samples linked to recurrence and immunotherapy outcomes using geometric deep learning.

154 citationstop 1%

humanspatial transcriptomics

𝕏 PostBluesky