Xinyue Li

SheepEpimap combines 516 histone CUT&Tag, ATAC-seq and RNA-seq datasets from 43 sheep tissues to annotate 2.93 million cis-regulatory elements and 145,407 allele-specific variants for trait interpretation.

The paper presents a multi-tissue sheep atlas identifying regulatory variants and their effects on molecular phenotypes, revealing allelic heterogeneity and evolutionary patterns.

The paper develops unsupervised methods to extract sleep and circadian features from wearable data, identifies 53 novel genetic loci associated with sleep, circadian rhythms, and related traits.

This paper introduces a penalized machine learning method to analyze circadian rhythms from wearable device data and links daily rhythms to motor development in infants.

The paper identifies hundreds of genes deregulated by SVs in cancer, showing increased expression linked to SV breakpoints and enhancer elements.