Author

Mian Gong

Aarhus UniversityORCID 0000-0002-1785-0621Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 10 Assay:bulk RNA-seq· 6 Assay:whole-genome sequencing· 5 Research Focus:eQTL / molecular QTL mapping· 4 Research Focus:gene regulatory network inference· 4 Organism:multiple species· 3 Research Focus:phylogenetics / evolution· 3 Organism:bacteria (other)· 2

Frequent Co-Authors

Lingzhao FangiD· 7 shared Weijie ZhengiD· 6 shared Bingxing AniD· 5 shared Dailu GuaniD· 5 shared Houcheng LiiD· 5 shared Ruidong XiangiD· 5 shared Xiaoning ZhuiD· 5 shared Bingjin LiniD· 4 shared

Activity by Year

2020-2026 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

7 shared papersGenetics

Lingzhao FangORCID

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

A multi-tissue epigenomic atlas links the sheep non-coding genome to domestication and complex traits

Zhu Meng, Shiwen Zhang, Ziyang Zhuang, Jiayi He, Fei Liu, Lingyun Wu, Xiangrong Sun, Jingsheng Lu, Xinyi Li, Hao Yang, Mian Gong, Xiaolong Du, Qiao Mei, Hao Li, Guoqing Zhang, , Zhangyuan Pan

SheepEpimap combines 516 histone CUT&Tag, ATAC-seq and RNA-seq datasets from 43 sheep tissues to annotate 2.93 million cis-regulatory elements and 145,407 allele-specific variants for trait interpretation.

bioRxiv · Aug 26, 2026 · PreprintGenetics✦ In-depth digest

Multi-layered molecular regulation of complex traits in an advanced intercross line

Xiaoning Zhu, Chenghao Zhai, Chong Li, Rongrong Liu, Hongmei Mou, Yunfei Zhu, Wei Luo, Peng Chen, Hanyu Wu, Yuzhan Wang, Kai Shi, Mian Gong, Weijie Zheng, Jian Ji, Chenglong Luo, , Yuzhe Wang

The paper maps a multi-layered molecular QTL atlas in chicken to understand complex trait regulation across tissues and developmental stages.

bioRxiv · Aug 21, 2026 · PreprintGenetics

Long-read RNA-seq resolves isoform-level and context-specific regulatory architecture of complex traits in cattle

Weijie Zheng, Q Zhang, Jinfeng He, Xiaoning Zhu, Mian Gong, Houcheng Li, Lin Liu, Li J, Zhu Ma, Bo Han, Yu Zhang, Jingsheng Lu, Bingjin Lin, Bingxing An, Zijiao Guo, , Sun D

The paper uses long-read RNA-seq to uncover isoform-level and context-specific regulatory effects in cattle, improving the resolution of molecular atlases and GWAS loci.

bioRxiv · Jun 5, 2026 · PreprintGenetics

The enhanced multi-tissue atlas of regulatory effects in cattle

Houcheng Li, Huicong Zhang, Di Zhu, Pengju Zhao, Zhenyu Wei, Jiaqi Lu, Mian Gong, Qi Zhang, Weijie Zheng, Xia Liu, Dailu Guan, Jinyan Teng, Qing Lin, Yongjie Tang, Yahui Gao, , Lingzhao Fang

The paper presents CattleGTEx, a resource characterizing regulatory effects in cattle, resolving GWAS signals and providing insights into adaptive evolution and selection.

bioRxiv · Mar 21, 2026 · PreprintGenetics

Sex-specific Genetic Regulatory Effects in Chickens

Haihan Zhang, Bingjin Lin, Yang Xi, Di Zhu, Chen Peng, Junhao Tu, Huichao Liu, Dailu Guan, Qingyuan Ouyang, Bogong Liu, Chenyu Fan, Zichao Song, Xing Meng, Houcheng Li, Bingxing An, , Xi He

The paper identifies sex-specific genetic regulatory effects in chickens using whole-genome sequencing and transcriptomes, revealing sex-dependent gene regulation and structural variants.

bioRxiv · Feb 28, 2026 · PreprintGenomics

A multi-tissue atlas of genetic regulatory effects in sheep

Mian Gong, Ziyang Zhuang, Xiangrong Sun, Yuan Xu, Huan-Huan Zhang, Yanan Wang, Dailu Guan, Ran Li, Xiaoning Lu, Zhonghao Bai, Pingjie Feng, Meiwen Song, Min Tian, Jingsheng Lu, Mingshan Wang, , Lingzhao Fang

The paper presents a multi-tissue sheep atlas identifying regulatory variants and their effects on molecular phenotypes, revealing allelic heterogeneity and evolutionary patterns.

bioRxiv · Nov 3, 2025 · PreprintGenomics

An atlas of cell type specific regulatory effects in cattle

Houcheng Li, Huicong Zhang, Pengju Zhao, Qi Zhang, Senlin Zhu, Tao Shi, Yanan Wang, Jing-Sheng Lu, Yang Liu, John Francis O'Grady, David Evan MacHugh, Yu Wang, Zhenyu Wei, Xuemei Lv, Ming-Shan Wang, , Lingzhao Fang

The paper constructs a cattle cell-type-specific regulatory variant atlas by integrating bulk and single-cell RNA-seq data, identifying eQTL and linking them to GWAS loci for breeding insights.

bioRxiv · Jun 23, 2025 · PreprintGenetics

The first sheep graph-based pan-genome reveals the spectrum of structural variations and their effects on tail phenotypes

Ran Li, Mian Gong, Xinmiao Zhang, Fei Wang, Zhenyu Liu, Lei Zhang, Qimeng Yang, Yuan Xu, Mengsi Xu, Huanhuan Zhang, Yunfeng Zhang, Xuelei Dai, Yuanpeng Gao, Zhuangbiao Zhang, Wenwen Fang, , Yu Jiang

The paper constructs a graph-based sheep pan-genome to identify structural variations and their association with tail phenotypes in domestic and wild sheep.

Genome Research · Mar 1, 2023Peer-reviewedGenomics

Ancient genomes redate the extinction of Sussemionus, a subgenus of Equus, to late Holocene

Dawei Cai, Siqi Zhu, Mian Gong, Naifan Zhang, Jia Wen, Qiyao Liang, Weilu Sun, Xinyue Shao, Yaqi Guo, Yudong Cai, Zhuqing Zheng, Wei Zhang, Songmei Hu, Xiaoyang Wang, He Tian, , Yu Jiang

The paper sequences ancient genomes of Sussemionus, re-dating its extinction to the late Holocene and revealing genetic divergence and admixture events in the Equus lineage.

eLife · May 11, 2022Peer-reviewedGenomics

The origin of domestication genes in goats

Zhuqing Zheng, Xihong Wang, Ming Li, Yunjia Li, Zhirui Yang, Xiaolong Wang, Xiangyu Pan, Mian Gong, Yu Zhang, Yingwei Guo, Yu Wang, Jing Liu, Yudong Cai, Qiuming Chen, Moses Okpeku, , Yu Jiang

This study identifies introgression and selection events in goat domestication, linking them to immune and behavioral genes.

Science Advances · May 20, 2020Peer-reviewedGenomics