This study identifies genetic variants associated with Alzheimer's disease and frontotemporal dementia in admixed Latin American populations using whole-genome sequencing and ancestry analysis.

npj Dementia · Jan 21, 2026Peer-reviewedGenetic & Genomic Medicine

Smaller limbic structures are associated with greater immunosuppression in over 1000 HIV-infected adults across five continents: Findings from the ENIGMA-HIV Working Group

Talia M. Nir, Jean‐Paul Fouché, Jintanat Ananworanich, Beau M. Ances, Jasmina M. Boban, Bruce James Brew, Linda Chang, Joga R. Chaganti, Christopher R. K. Ching, Lucette A. Cysique, Thomas Ernst, Joshua Faskowitz, Vikash Gupta, Jaroslaw Harezlak, Jodi M. Heaps‐Woodruff, , for the ENIGMA-HIV Working Group

This study finds smaller limbic brain volumes are associated with greater immunosuppression in HIV+ adults across five continents.

bioRxiv · Aug 5, 2019 · PreprintNeuroscience

Predicting neurodevelopmental outcomes in children with perinatal HIV using a novel machine learning algorithm

Robert H. Paul, Kyu Cho, Claude A. Mellins, Kathleen Malee, Reuben N. Robbins, Stephen John Kerr, Jiratchaya Sophonphan, Neda Jahanshad, Linda Aurpibul, Kulvadee Thongpibul, Pope Kosalaraksa, Suparat Kanjanavanit, Chaiwat Ngampiyaskul, Wicharn Luesomboon, Jurai Wongsawat, , on behalf of the PREDICT Study Group

The paper uses machine learning to predict neurocognitive outcomes in children with perinatal HIV, identifying key predictors from clinical data with high accuracy.

bioRxiv · May 9, 2019 · PreprintNeuroscience