Author
University of California, San FranciscoORCID 0009-0006-7848-5177Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Mackenzie Welch, Paul J. Sampognaro, Shunpan Shu…·Aimee W. Kao
The paper identifies PQLC2 as a lysosomal pH regulator that affects tau homeostasis through a CRISPRi screen in iPSC-derived neurons.
Michael C Okorie, Caroline Jonson, Alexis P. Oddi…·for the Alzheimer's Disease Sequencing Project and the Healthy Aging Brain Study—Health Disparities
This paper evaluates cross-ancestry polygenic risk scores (PRS) for Alzheimer's disease across multi-ethnic populations, finding improved predictive accuracy in non-European groups.
Samantha K. Swift, Guangming Huang, J. Nicholas Cochran…·Celeste M M. Karch
The paper identifies NINL as a modulator of tau aggregation through integrative genomic and functional analyses linking it to proteostasis dysfunction in FTD and AD.
Juliana Acosta‐Uribe, Stefanie Danielle Piña‐Escudero, J. Nicholas Cochran…·Jennifer S. Yokoyama
This study identifies genetic variants associated with Alzheimer's disease and frontotemporal dementia in admixed Latin American populations using whole-genome sequencing and ancestry analysis.
Iris Broce, Daniel W. Sirkis, Ryan M. Nillo…·Jennifer S. Yokoyama
The paper identifies a C9orf72 gene network correlated with cortical thickness in C9-FTD and implicates vulnerable cell types.