Promoter mutagenesis and a massively parallel reporter screen of the MAPT locus identifies cis-regulatory elements and genetic variation effects
Rebecca M. Hauser, Henry L. Limbo, J. Nicholas Brazell…·J. Nicholas Cochran
The paper identifies cis-regulatory elements and genetic variation effects in the MAPT locus using MPRA and CRISPRi in neuronal and HEK293FT cells.