Distributed activity in the human posterior putamen distinguishes goal-directed from habitual control
Amogh Johri, Lisa Marieke Kluen, Rani Gera, Vincent Y. Man, Omar David Perez, Julia Pia Simon, Weilun Ding, Aniek Fransen, Scarlet J. Cho, Sarah Oh, Jeffrey Cockburn, Jamie D. Feusner, Reza Tadayonnejad, John P. O’Doherty
The paper uses fMRI decoding to show that neural activity in the posterior putamen during learning predicts individual differences in habit versus goal-directed behavior across multiple cohorts.
bioRxiv · Nov 26, 2025 · PreprintNeuroscience