Author

Dandan Peng

University of Southern CaliforniaORCID 0000-0003-2006-0804Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Dandan Peng1 paper · Children's Hospital of Zhejiang University

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Organism:human· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Michael D. EdgeiD· 2 shared Arbel HarpakiD· 1 shared Ben WeisburdiD· 1 shared Bida GuiD· 1 shared Christy W. LaFlammeiD· 1 shared Hakhamanesh MostafaviiD· 1 shared Heather C. MeffordiD· 1 shared Jeremy J. BergiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenetics

Michael D. EdgeORCID

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3 papers

Recent·Most cited

Evaluating ARG-estimation methods in the context of estimating population-mean polygenic score histories

Dandan Peng, Obadiah Mulder, Michael D. Edge

The paper benchmarks ARG estimation methods for their performance in estimating population-mean polygenic score histories using simulated data.

Genetics · Feb 25, 2025Peer-reviewedGenetics

A Litmus Test for Confounding in Polygenic Scores

Samuel Pattillo Smith, Olivia S. Smith, Dandan Peng, Xinyi Miao, Hakhamanesh Mostafavi, Jeremy J. Berg, Michael D. Edge, Arbel Harpak

This paper introduces PGSUS, a method to assess the influence of stratification and assortative mating effects on polygenic scores, revealing that direct genetic effects often contribute little to PGS variation.

bioRxiv · Feb 1, 2025 · PreprintGenomics

A population-scale map of human tandem repeat composition and mutation dynamics from long-read assemblies

Bida Gu, Dandan Peng, Christy W. LaFlamme, Mark F. Bennett, Melanie Bahlo, Ben Weisburd, Heather C. Mefford, Mark Chaisson

The paper constructs TRCompDB, a database of 4.4 million tandem repeat loci across 832 human genomes, revealing mutation rates and dynamics influenced by recombination and duplication context.

bioRxiv · Aug 7, 2024 · PreprintBioinformatics