Cancer BiologybioRxivPreprint
Ophiobolin A selectively alters mitochondria, metabolism and redox biology in breast cancer and mammary epithelial cells which have undergone epithelial to mesenchymal transition
Haleigh N. Parker, Yongfeng Tao, Jenna Tobin…·Joseph H. Taube
This study identifies ophiobolin A's mechanism of action against EMT-positive breast cancer cells, showing mitochondrial and metabolic disruption with antioxidant countermechanisms.
DOI 10.1101/2025.04.08.647828