Author

Jenna Tobin

Baylor University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander KornienkoiD· 2 shared Angela BoariiD· 2 shared Antonio EvidenteiD· 2 shared Daniel RomoiD· 2 shared Joseph H. TaubeiD· 2 shared Kayla L. HabermaniD· 2 shared A. J. Martinez· 1 shared Alagu SubramanianiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Alexander KornienkoORCID

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2 papers

Recent·Most cited

Ophiobolin A selectively alters mitochondria, metabolism and redox biology in breast cancer and mammary epithelial cells which have undergone epithelial to mesenchymal transition

Haleigh N. Parker, Yongfeng Tao, Jenna Tobin, Kayla L. Haberman, Samantha J. Davis, Emily R. York, A. J. Martinez, Nobuyuki Matsumoto, Jaquelin Aroujo, Jun Hyoung Park, Bernd Zechmann, Benny Abraham Kaipparettu, Angela Boari, Christie Maria Sayes, Antonio Evidente, , Joseph H. Taube

This study identifies ophiobolin A's mechanism of action against EMT-positive breast cancer cells, showing mitochondrial and metabolic disruption with antioxidant countermechanisms.

bioRxiv · Apr 8, 2025 · PreprintCancer Biology

PANoptosis, a combination of inflammatory cell death mechanisms, induced 1 by Ophiobolin A in breast cancer cell lines

Santhalakshmi Ranganathan, Tolulope Ojo, Alagu Subramanian, Jenna Tobin, Kayla L. Haberman, Alexander Kornienko, Angela Boari, Antonio Evidente, Mary Lauren Benton, Daniel Romo, Joseph H. Taube

This study shows that ophiobolin A induces PANoptosis in breast cancer cells through RIPK1-dependent mechanisms, leading to lytic and pro-inflammatory cell death.

bioRxiv · Apr 8, 2025 · PreprintCancer Biology