Osvaldo Espin‐Garcia

The paper identifies donor cell attributes and patient features that correlate with response to mesenchymal stromal cell (MSC) injections in knee osteoarthritis patients.

The paper assesses T-cell dynamics in pediatric cancer patients during treatment, finding that immune checkpoint proteins and T-cell subsets change with therapy, and introduces a Dynamic Immunogenomic Score to predict relapse risk.

This paper develops a joint model to identify direct and indirect genetic associations of SNPs with time-to-event traits in longitudinal studies, demonstrating improved accuracy in disease progression analysis.

The paper proposes two-phase sampling strategies for post-GWAS fine-mapping studies to improve power and efficiency while controlling type 1 error.

The paper compares data integration methods in GWAS using functional annotations, finding that weighted p-value methods identify more variants than sFDR, though sFDR is more robust to uninformative scores.