Author

Alice Boo

Imperial College LondonORCID 0000-0003-2059-614XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Guy-Bart V. StaniD· 2 shared Ali R. AwaniD· 1 shared Charlie GilbertiD· 1 shared Francesca CeroniiD· 1 shared Harman MehtaiD· 1 shared Olivier BorkowskiiD· 1 shared Rodrigo Ledesma‐AmaroiD· 1 shared Simone FuriniiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSynthetic Biology

Guy-Bart V. StanORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintMay 15, 2023

Host-aware RNA-based control of synthetic microbial consortia

Alice Boo, Harman Mehta, Rodrigo Ledesma‐Amaro, Guy-Bart V. Stan

This paper develops an RNA-based feedback control system to stabilize microbial consortia composition without using toxins or syntrophy.

14 citations

E. coliexperimental assay

𝕏 PostBluesky

Synthetic BiologyNature MethodsPeer-reviewedMar 26, 2018

Burden-driven feedback control of gene expression

Francesca Ceroni, Alice Boo, Simone Furini…·Tom Ellis

The paper identifies heat-shock promoters that activate rapidly in response to synthetic gene expression in E. coli and uses them to build a CRISPR/dCas9-based feedback system that improves protein yield by adjusting synthetic construct expression based on cellular burden.

374 citationstop 1%

E. colibulk RNA-seq

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