Elena Z. Alkalaeva

This study investigates how PDCD4 modulates translation initiation and termination by interacting with multiple factors, revealing stage-specific regulation and additive effects on peptide release.

The paper identifies the amino acid preceding a premature termination codon as a key determinant of nonsense-mediated mRNA decay efficiency.

This study shows that eIF4F and eIF4B enhance translation termination by promoting eRF1 loading and eRF3 GTPase activity in a closed-loop mRNA structure.

This study shows that SARS-CoV-2 Nsp1 stimulates host translation termination by interacting with eRF1 and promoting release factor activity.

The paper investigates how specific 3' contexts around stop codons affect translation termination in eukaryotes, showing ribosomes can recognize these contexts and stimulate readthrough.