Author

Isabelle Plante

Institut National de la Recherche ScientifiqueORCID 0000-0003-2080-6450Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Organism:rat· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

Alec McDermottiD· 3 shared David Tovar‐ParraiD· 3 shared Arash AghighiD· 2 shared Bhawna Dhawan· 2 shared Étienne Audet‐WalshiD· 2 shared Fabien JoaoiD· 2 shared François LégaréiD· 2 shared Géraldine DelbèsiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPharmacology & Toxicology

Alec McDermottORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyToxicological SciencesPeer-reviewedMay 1, 2026

Late gestational exposure to flutamide alters stromal composition and immune landscape in the rat mammary gland during pre-puberty, peri-puberty, and adulthood

David Tovar‐Parra, Alec McDermott, Jysiane Cardot…·Isabelle Plante

This study shows that prenatal exposure to flutamide alters mammary gland stromal composition and immune landscape in rats across multiple developmental stages.

DOI 10.1093/toxsci/kfag053

ratbulk RNA-seq

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Cell BiologyBiology Methods and ProtocolsPeer-reviewedJan 1, 2026

Gap junction communication regulates luminal-myoepithelial crosstalk and cell differentiation in a bi-layered human mammary epithelial cell model

Alec McDermott, Melany Nicole Juarez, David Tovar‐Parra…·Isabelle Plante

This study develops a bilayered co-culture model of human mammary epithelial cells and shows that gap junction communication is essential for lineage-specific differentiation.

DOI 10.1093/biomethods/bpag031

humanbulk RNA-seq

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Pharmacology & ToxicologyToxicological SciencesPeer-reviewedNov 7, 2025

An in utero exposure to the synthetic estrogen diethylstilbestrol affects the fat pad composition in post-natal mammary glands

David Tovar‐Parra, Alec McDermott, Jysiane Cardot…·Isabelle Plante

This study shows that in utero exposure to diethylstilbestrol alters mammary gland stromal and immune features across development, leading to long-term changes in extracellular matrix and inflammation.

1 citation

ratbulk RNA-seq

𝕏 PostBluesky