Mikhail E. Kandel

This paper introduces SEEQPI, a label-free imaging technique that enables subcellular resolution and deep imaging in turbid tissues, demonstrating its application in organoids and mouse brains.

The paper uses label-free interferometric imaging to show that hippocampal astrocyte volume decreases by 25% during the night while maintaining constant dry mass.

The paper quantifies myelin content in brain tissue using cSLIM, showing differences between AGA and SGA piglets and the effect of diet on myelination.