Megan P. Corbett

This study compares the biology and genetic drivers of human and canine invasive urothelial carcinoma, finding shared cellular organization but distinct mutations and platform effects in organoids.

The paper develops chicken lung organoids to model avian influenza virus-host interactions and finds they contain diverse cell types and express relevant viral infection genes.

This paper establishes a canine urothelial carcinoma organoid repository for comparative and translational carcinoma studies, showing genomic and transcriptomic fidelity to tissue and potential for drug testing.

The paper uses spatial imaging and organoid models to identify therapy-resistant CD44v9+ cancer stem cells in PDAC and show that cabozantinib may enhance immunotherapy by altering the tumor microenvironment.

This study identifies higher frequencies of specific histologic subtypes and divergent differentiation in canine urothelial carcinoma compared to previous reports, suggesting dogs as a model for human sarcomatoid UC.

The paper uses phase imaging combined with AI to quantify myelin content in brain tissue, showing high accuracy in distinguishing gestational size and diet type.

The paper quantifies myelin content in brain tissue using cSLIM, showing differences between AGA and SGA piglets and the effect of diet on myelination.