Author

Vesna Šendula Jengić

ORCID 0000-0003-2126-3793Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 1

Frequent Co-Authors

Lucija OstojićiD· 1 shared Željko M. SvedružićiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperNeuroscience

Lucija OstojićORCID

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1 paper

Recent·Most cited

NeuroscienceInternational Journal of Molecular SciencesPeer-reviewedJan 17, 2023

Binding of different substrate molecules at the docking site and the active site of γ-secretase can trigger toxic events in sporadic and familial Alzheimer's disease

Željko M. Svedružić, Vesna Šendula Jengić, Lucija Ostojić

The paper shows that γ-secretase saturation with substrates leads to toxic effects in Alzheimer's disease by disrupting presenilin structures and increasing Aβ-protein production.

5 citations

statistical model

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