Kaïdre Bendjama

This study identifies conserved T-cell targets across betacoronaviruses using machine learning and validates their immunogenicity through functional assays and mRNA vaccination in mice.

This paper introduces TCRPPO2, an AI-driven framework for optimizing TCR affinity, showing improved activity in engineered TCRs against tumor antigens.

BERTMHC improves MHC class II peptide binding prediction using a transformer model and multiple instance learning, outperforming existing methods.